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By the pancreas called insulin. Metformin works by helping to restore your body's proper response to the insulin you naturally produce, and by decreasing the amount of glucose you absorb from your food and the amount of sugar in your blood. Glucophage lowers the amount of glucose made by your liver. Insulin, to treat type 2 diabetes. Glucophage tablets are standard release tablets that are taken two or three times a day either during or just after meals.
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