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Patients with hepatic function impairment may have increased Topiramate plasma concentrations and a dosage adjustment may be needed. You may take Topiramate with you usual meals. Topiramate, which was originally used for seizures but now is mostly used for migraine prevention, has been found to increase a person's risk of getting kidney stones. Patients with hepatic function impairment may have increased Topiramate plasma concentrations and a dosage adjustment may be needed. Many people with migraines experienced significantly fewer attacks, enabling them to help manage their condition. Clinical trials found that patients receiving the recommended daily dose of Topamax experienced a significant reduction in monthly migraine attacks, compared with placebo. Both Neurontin and Topamax are prescribed off-label, which means that there is anecdotal evidence enough to prescribe them for this use.
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