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Prednisone fat redistribution: "You could have unpleasant withdrawal symptoms. Prednisolone is a corticosteroid used to treat various inflammatory and allergy conditions as well as other diseases. Steroid medication needs may change if you have surgery or a medical emergency. Do not stop using Prednisolone suddenly, or you could have unpleasant withdrawal symptoms. Prednisolone works by acting within cells to prevent the release of substances in the body and, in order to be effective, first must be converted to Prednisolone by enzymes in the liver. Prednisone is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of cortical. Prednisone and Prednisolone are considered to be intermediate acting steroids, meaning that a dose lasts about a day or a day and a half."